Example sentences for: unglycosylated

How can you use “unglycosylated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The unglycosylated form of fibronectin is more susceptible to proteolytic degradation than the glycosylated form [ 41 ] . It will be interesting to determine why two forms of myocilin are secreted in humans and what functionality, if any, N-linked glycosylation imparts on human vs. rabbit myocilin.

  • We show that, in Xenopus oocytes, VR1 is expressed in both glycosylated and unglycosylated forms, with ~4 kDa difference in their apparent molecular weights.

  • N-linked glycosylation is known to confer stability on many extracellular proteins [ 40 ] . Myocilin is similar to fibronectin (an extracellular matrix protein) in that both a glycosylated and unglycosylated form is secreted from the cell.

  • Several groups have shown that myocilin is glycosylated [ 10 16 17 18 19 20 21 ] whereas one group suggests that myocilin is not glycosylated [ 22 ] . In our hands, both an N-linked glycosylated (≈57-kDa) and unglycosylated (≈55-kDa) form of myocilin is detected in TM cell culture media [ 17 ] and aqueous humor [ 12 ] . The basis for both secretion and N-linked glycosylation of myocilin is part of the focus of this paper.

  • These data indicate that wild-type VR1 channels expressed in Xenopus oocytes are present in both unglycosylated and glycosylated forms and that the N-linked glycosylation occurs at position 604.


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