Words similar to unduplicated

Example sentences for: unduplicated

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Additionally, however, we found that paralogs evolve significantly faster than unduplicated genes with a similar level of divergence, which is compatible with the notion that gene duplications are a source of new protein functions.
It associates specifically with unduplicated centrosomes, and its phosphorylation by CDK-2/cyclin E, the trigger for centrosome duplication, is required for duplication to occur [ 17 ] . The nucleophosmin gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase in cases of this disease with (2;5)(p23;q35) translocations [ 18 ] . The nucleophosmin portion contributes to transformation by providing a dimerization domain, which allows activation of the fused kinase and signal transduction [ 19 ] .
The second hypothesis holds that a gene duplication that leads to a new function is preceded by a period of 'gene sharing', such that the original, unduplicated gene encodes two distinct functions.
Each of these differences in the functional composition of the sets of paralogs and unduplicated genes were statistically highly significant (p < 0.0001, χ 2test).
The present observation that duplicated genes experience a substantial relaxation of selection compared to unduplicated genes is compatible with the traditional view that gene duplications make a major contribution to the evolution of new gene functions.