Words similar to undifferentiated
Example sentences for: undifferentiated
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Undifferentiated hESCs, H1 (WA-01, XY, passages 40–65) and H9 (WA-09, XX, passages 35–45), were cultured on mitotically inactivated mouse embryonic fibroblasts (Specialty Media, Phillipsburg, New Jersey, United States) and maintained under growth conditions and passaging techniques described previously [3].
ID2 was recently shown also to be a target of activated β-catenin in colon carcinoma cells [ 13 ] . It is a general inhibitor of the bHLH proteins such as MyoD and E12/E47 [ 14 ] and can interact with the tumor suppressor RB1 [ 15 ] . MSX1 expression can revert differentiated myotubes into an undifferentiated state [ 16 ] . REST/NRSF is known to block neural differentiation by binding to and inhibiting the expression of neuronal genes [ 17 18 ] . To what extent these genes are controlled by Wnt signaling in intact animals or in other cell types is not clear yet, but we do note that MSX mutants have phenotypes similar to LEF/TCF mutants [ 19 20 ] .
One concern for the clinical application of hESC-derived progeny in regenerative medicine is the risk of teratoma formation due to the presence of residual undifferentiated ES cells among the differentiated progeny.
Line B also grows faster than wild-type over the first 4-6 days, but subsequently its growth slows and is considerably retarded compared to undifferentiated cells (Fig.
Comparison of the TBP and TAF II 135 levels in extracts from day 7 differentiated cells prepared in the presence of MG132 showed that they were indeed significantly reduced compared to undifferentiated cells or day 3 differentiated cells (approximately 3 fold, Fig.
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