Words similar to undernutrition
Example sentences for: undernutrition
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Moreover, maternal nutrient restriction during the middle third of gestation in pigs had no effect on ovarian progesterone production or fetal survival [ 46 ] . Morphometric data for sheep corpora lutea are consistent with previous reports summarized by Sawyer [ 23 ] . It therefore appears that maternal ovaries are comparatively resilient to repercussions of undernutrition.
That maternal undernutrition can affect fetal ovarian development has been documented [ 1 ] . Experiments using the sheep as a paradigm indicate that meiotic maturation of germ cells is delayed by feed restriction [ 2 3 ] ; putative molecular mechanisms which mediate this effect are unknown.
Levels of p53 in maternal oocytes were not altered overall (irrespective of follicular classification) by undernutrition (Figure 2); and therefore, we did not monitor the inductive damage (8-oxoguanine) or response survival (Bcl-2)/repair (polymerase β) markers.
There is a lack of fundamental information on potential influences of undernutrition on the functional morphology of ovaries of pregnant animals.
In fact, the apoptotic demise (yielding double-stranded DNA breaks) of female germ cells throughout gestations of most vertebrates will encompass more than one-half of precursor populations [ 38 39 ] . Day 75 is the approximate time-point when a maximum number of oogonia is achieved in lambs; a nearly five-fold loss then occurs between Days 75 and 90 [ 40 ] . In some cases of nutritional deprivation cellular losses are accelerated [ 38 ] and reproductive performance of the female offspring during adulthood is attenuated [ 1 ] . Prenatal exposure to famine (1944-45 Dutch cohort) did not affect subsequent fertility of women [ 41 ] . Numbers of oogonia/oocytes and weights of mid-gestational fetal ovaries of sheep were increased [ 2 42 ] or not influenced by undernutrition [ [ 3 ] , present study].
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