Example sentences for: underestimation

How can you use “underestimation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although there is debate regarding the level of cancer risk associated with mutations in BRCA1 and the significance of the lack of mutations in sporadic tumors, it is possible that alterations in the function of BRCA1 may occur by mechanisms other than mutation, leading to an underestimation of risk when it is calculated solely on the basis of mutational analysis.

  • In recognition of the seriousness of the problem, over 100 million dollars has been set aside to fund the Canadian Diabetes Strategy - a comprehensive national plan focusing on the prevention of diabetes through health promotion and education [ 1 ] . Targeting diabetes in this way is not surprising as it has been estimated that over 1 million Canadians are known to be afflicted with this condition, with 90% having type 2 diabetes [ 2 ] . Furthermore, it is acknowledged that this is likely an underestimation of the scope of the disease as up to 1 in 2 persons with diabetes do not know they have it [ 3 ] .

  • Although this reproducibility is somewhat lower than in other studies, a non-differential misclassification of menarcheal age would have resulted in an underestimation of the actual associations.

  • Other recent studies suggest that these numbers may be an underestimation and that the human genome appears more complicated [ 4 ] . Understanding the functions of such a large number of genes has been an unprecedented challenge for functional genomics research.

  • Furthermore, when the calibration curves are examined there is no consistent pattern of overestimation or underestimation of mortality among the four systems in the different strata of severity of illness.


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