Example sentences for: ultra-rapid

How can you use “ultra-rapid” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Drug block of the voltage-gated potassium channels that conduct the ultra-rapid delayed rectifier current I Kur is associated with increased intracellular potassium concentration, increased cell volume, activation of chloride influx and hyperpolarization of resting membrane potential.

  • Voltage-gated K +currents with distinct electrophysiological and pharmacological properties are present in granulosa cells (GC), and modulate resting membrane potential [ 4 12 13 16 17 ] . Furthermore, selective antagonism of GC K +channels with distinct molecular correlates, electrophysiological properties and expression patterns can influence differentially GC proliferation, steroidogenic capability, and apoptosis [ 17 18 ] . Our laboratory has previously identified two distinct delayed rectifier K +currents in pig GC: a slow current (I Ks ) associated with channels formed by co-assembly of KCNQ1 pore-forming and KCNE1 accessory proteins, and an ultra-rapid current (I Kur ) formed by co-assembly of KCNA pore-forming and KCNAB accessory proteins [ 4 ] . Moreover, we have shown that selective block of I Ks enhances basal progesterone synthesis, while complete block of both I Ks and I Kur accelerates apoptosis [ 18 ] .

  • The data demonstrate that PGC-2 cells express K +currents similar to the granulosa cell ultra-rapid delayed rectifier current (I Kur ) in terms of the voltage-dependence and kinetics of activation and deactivation, as well as the sensitivity to 4-AP.


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