Example sentences for: tyr

How can you use “tyr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If QUASI rejects the (Jukes-Cantor) neutral drift null hypothesis because the observed R:S is significantly higher than one, then QUASI classifies this replacement mutation (Tyr) as positively selected.

  • One of these mutations is ttt→tat (Tyr).

  • This binding site coincides with that of AChBP, and is in agreement with photo-affinity labeling and mutagenesis study [ 6 11 ] . The ligand makes Van der Waals contact with Trp182, Tyr230 and Cys225-226 of alpha4, and Trp82, Leu146 and Phe144 of beta2 (Figure 3- Top).

  • The substrate-binding model showed that Tyr228 in L1 was position-conserved with Asn233 in the other crystallographically characterized metallo-β-lactamases [ 37 42 44 45 46 ] . Spencer and coworkers postulated that Tyr228 is part of an oxyanion hole that interacts with the β-lactam carbonyl on substrate and helps to stabilize the putative tetrahedral intermediate formed during substrate turnover [ 37 ] . To test this hypothesis, Tyr228 was changed to an alanine and to a phenylalanine to afford the Y228A and Y228F mutants, respectively.

  • 32P-labelled histone was prepared by phosphorylation with PKA in the presence of γ- 32P [ATP] essentially as described, followed by removal of the free ATP by gel filtration [ 19 52 ] . The resultant phosphohistone is exclusively phosphorylated at Ser residues [ 53 ] . 32P-labeled peptide EAI(Yp)AAPFAKKK, phosphorylated at the single Tyr residue by pp43 v-ablkinase, was prepared essentially as described [ 19 52 ] . Phosphatase reactions were initiated by the addition of the substrate.


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