Example sentences for: tyr

How can you use “tyr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The p51 subunit is generated via endoproteolytic cleavage of the p66 subunit between Phe 440 and Tyr 441 [ 5 6 ] . The larger subunit (p66) contains both polymerase and RNase H activities, while the smaller subunit (p51) lacks these functions, in context of the heterodimer [ 7 8 ] . However, both the p66 and p51 monomers are functionally inactive when dissociated from each other [ 9 ] . Several years have passed since it was first suggested that agents that could specifically disrupt the dimerization of HIV-1 RT might prove a worthwhile antiretroviral strategy [ 10 ] , though such agents have yet to be developed.

  • Strikingly, the nematode protein has greatest similarity (56% amino-acid identity) to GSI from the rhizobial bacterium, Mesorhizobium loti , including conservation of Tyr397.

  • This catenation activity observed with topoisomerase I and Top67 was unlikely to be due to contaminating topoisomerase III activity since it was not observed with the ZD domain purified under almost identical procedures and a site-directed mutant with substitution of the active site Tyr319 by phenylalanine also did not exhibit this activity (Figure 6a).

  • It has been established that, to achieve its maximal transcriptional activity, STAT1 must be phosphorylated on both Tyr701 and Ser727 [ 32 ] . Phosphorylation of STAT1 on Ser727 occurs in response to LPS, UV irradiation and other agents that activate the p38MAPK pathway [ 33 ] . As phorbol esters can also stimulate the MAPK cascade through activation of PKC [ 34 ] , it is tempting to speculate that combined treatment of cells with PMA and IFNg could increase the pool of STAT1 molecules phosphorylated on both Tyr701 and Ser727.

  • The expected S is one because only one mutation (ttc) is silent, and the expected R is also one because only one point mutation of ttt (tat) codes for Tyr, so the expected R:S is one, in this case.


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