Words similar to tyr
Example sentences for: tyr
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If QUASI rejects the (Jukes-Cantor) neutral drift null hypothesis because the observed R:S is significantly higher than one, then QUASI classifies this replacement mutation (Tyr) as positively selected.
This binding site coincides with that of AChBP, and is in agreement with photo-affinity labeling and mutagenesis study [ 6 11 ] . The ligand makes Van der Waals contact with Trp182, Tyr230 and Cys225-226 of alpha4, and Trp82, Leu146 and Phe144 of beta2 (Figure 3- Top).
The proteins were transferred to nitrocellulose paper, and incubated at room temperature for 3 hours, or overnight, at 4°C, with mouse monoclonal anti-human Mcl-1 (1:1000), p38 MAP kinase, phosphoinositide 3 kinase (PI3K), or protein kinase B-alpha (PKB-α) (1:500) antibodies (Transduction Laboratories, San Diego, CA, USA and New England Biolabs, Inc., Beverly, MA, USA), or rabbit polyclonal anti-rat p44/42 MAP kinase (1:1000), or doubly phosphorylated anti-human Thr180/Tyr182 phospho-p38 MAP kinase (1:1000) antibodies (New England Biolabs, Inc.).
The gametogenesis was confirmed by the appearance of Pfg27, an early gamete-specific protein [ 30 ] . Having demonstrated that the monoclonal antibody was specific for PP1, we used it in an attempt to inhibit PfPP1 activity in vitro . At optimal concentrations, the antibody almost completely inhibited (90% inhibition) recombinant PfPP1 (including its Tyr phosphatase activity), and also inhibited the phosphatase activity of the P. falciparum extract by about 70% (data not shown).
In 2 month old mice, homozygosity for Tyr c -2 J resulted in increased IOP (14.