Example sentences for: twofold

How can you use “twofold” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, nearly 800 probe sets showed a greater than twofold increase on average from A549 culture profiles to A549 xenograft tumor profiles.

  • In contrast, the expression profiles of tumors 7 and 9 showed marked differences from that of tumor 5A (correlation coefficients of 0.787 for tumors 5A and 7, and 0.745 for tumors 5A and 9), with the expression of 1937 (tumors 5A and 7) and 1764 (tumors 5A and 9) genes differing by twofold or greater between tumors.

  • One might wonder how that's possible, given the plethora of meeting places most big cities offer my age group, but my troubles are twofold.

  • The use of a higher criterion (that is, threefold) excluded some genes, such as those for MCP-1 and ICAM-1, which are known to be regulated in the acute phase of allergen challenge [ 15, 16]; on the other hand, a lower criterion, such as twofold, increased the probability of false-positive genes and lack of confirmation by RT-PCR (see Validation of the microarray gene expression, below).

  • The advantage here is twofold: the isolation of the intracellular signal removes apoplastic tracer from the data; and, in contrast to other NMR methods using shift reagents, the movement of any small molecule that gives an NMR signal can be followed (this includes any molecule containing carbon, nitrogen or nonlabile hydrogen atoms).


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