Example sentences for: two-hit

How can you use “two-hit” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If inactivation of these genes is a random process, it was understandable that people who inherit an inactivated copy of a tumour suppressor gene had a higher risk of developing the associated form(s) of cancer than people born with two normal copies, as postulated in Alfred Knudson's (1971) two-hit model.

  • According to the two-hit model, it was expected that in these tumours this copy would have been lost or inactivated.


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