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Example sentences for: ttgtccaca

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The relative gene order in this region is also highly conserved in many bacteria, especially the Gram-positives [ 11 ] . Although intergenic sequences in this region are conserved only among closely related organisms, the DnaA box is found in the non-coding regions flanking dnaA in most bacteria studied [ 12 ] . DnaA boxes are conserved nucleotide sequences (TTGTCCACA) where the DnaA protein binds to DNA, triggering events that ultimately lead to replication initiation and DNA synthesis [ 9 ] .
The Gram-positive organisms in this study harbor 10 - 30 DnaA boxes (with 1 - 3 mismatches from the consensus sequence TTGTCCACA) flanking the dnaA sequence [ 8 20 21 22 23 ] and 35 were found surrounding the M. paratuberculosis dnaA gene (Fig.