Words similar to trma

Example sentences for: trma

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Surprisingly, mitochondria derived from TRMA lymphoblasts lacked the high affinity uptake of thiamine.
Mitochondria isolated from TRMA lymphoblasts took up ThDP in an essentially identical saturable, biphasic fashion as uptake by normal mitochondria (fig.
Interestingly, ThDP-utilizing enzymes in mitochondria are much less affected (as revealed by loss of activity) upon progressive depletion of thiamine available to TRMA cells than are ThDP-utilizing enzymes of the cytosol [ 6 ] . For these reasons, we have examined the uptake of thiamine and especially ThDP by mitochondria from several human cell types, including cells from TRMA patients.
Normal lymphoblasts, TRMA lymphoblasts and fibroblasts cell lines were obtained and have been characterized as described [ 6 ] . The human neuroblastoma cells were an SY-SY5Y cell line, a thrice-cloned subline of SK-N-SH [ 24 ] . GlyB cells, a Chinese hamster ovary K1 subline, are deficient in the transport of folate into mitochondria [ 23 ] and were a kind gift from L. Chasin (Columbia University).
The antiserum detects a protein of 55 KD (predicted size of the plasma membrane thiamine transporter) that is not detected in cells from TRMA individuals that possess a premature stop codon within the transporter gene (unpublished results).