Words similar to trisphosphate
Example sentences for: trisphosphate
How can you use “trisphosphate” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, PTEN's protein phosphatase activity is able to down-regulate focal adhesion kinase (FAK) phosphorylation, which leads to the inactivation of the Ras/MAP kinase pathway [ 19 20 21 ] . Second, its lipid phosphatase activity targets the second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] and thereby blocks activation of the protein kinase B (PKB/Akt) pathway [ 11 18 22 23 24 ] . Whereas both of the above pathways are intimately involved in the control of cell growth and survival, PTEN-regulated FAK activity further appears to impinge on cell adhesion, cell migration, and cell invasion [ 20 21 ] . It therefore emerges that the loss of PTEN activity may confer increased survival ability, proliferative potential, and invasive capacity on cells, and thereby may promote progression towards a more malignant phenotype.
The resolution of the discordant results for inositol-1,4,5-trisphosphate receptor, H +-ATPase, branched aminotransferase and epoxide hydrolase is presented in Figure 5b.
Phosphatidylinositol-(3,4,5)-trisphosphate (PIP3) is one of the major intracellular second messengers regulating growth, metabolism and vesicular trafficking [for reviews see refs [ 1 2 3 ] ]. The level of (PIP3) in the cell is determined by the balance of kinase and phosphatase activity.
PI 3-kinase induces Btk membrane targeting by generating phosphatidylinositol 3,4,5-trisphosphate (PIP3) to which the PH domain of Btk binds.
Analysis of the discordant oligonucleotide sequences (that is, inositol-1,4,5-trisphosphate receptor, H +-ATPase, branched aminotransferase and epoxide hydrolase) did not reveal any obvious secondary structure that might interfere with hybridization.
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