Words similar to trimer

Example sentences for: trimer

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In fact, the only two positively selected variants QUASI identifies in site D are solvent-exposed at the extreme edge of the HA trimer (Fig.
A "non-neutralizing" face has been identified where binding Abs generally do not neutralize HIV when gp120 is oligomerized [ 45, 47]; these data were interpreted as indicating that the non-neutralizing face is occluded in the trimer and that binding Abs are raised against shed gp120 monomers.
The conformational changes lead to the formation of a coiled-coil in gp41, consisting of three NH 2 -terminal leucine/isoleucine zipper regions, each contributed by one of the three subunits of the envelope glycoprotein trimer.
In the fully assembled HA protein, site D is buried in the trimer interface and therefore is not generally accessible to Ab [ 41, 42].
Thus, because positively selected gp120 variants found throughout gp120 may be selected by T-cell immunity, QUASI's finding that the non-neutralizing face includes positively selected variants is not at odds with models where the non-neutralizing face forms the gp120 trimer interface.