Words similar to trimer
Example sentences for: trimer
How can you use “trimer” in a sentence? Here are some example sentences to help you improve your vocabulary:
The conformational changes lead to the formation of a coiled-coil in gp41, consisting of three NH 2 -terminal leucine/isoleucine zipper regions, each contributed by one of the three subunits of the envelope glycoprotein trimer.
Thus, because positively selected gp120 variants found throughout gp120 may be selected by T-cell immunity, QUASI's finding that the non-neutralizing face includes positively selected variants is not at odds with models where the non-neutralizing face forms the gp120 trimer interface.
A "non-neutralizing" face has been identified where binding Abs generally do not neutralize HIV when gp120 is oligomerized [ 45, 47]; these data were interpreted as indicating that the non-neutralizing face is occluded in the trimer and that binding Abs are raised against shed gp120 monomers.
At the time that the antigenic sites were proposed, residues in and around the trimer interface were variable and found on the monomer surface, so they were grouped and labeled as antigenic site D even though it was unclear how site D was recognized by Ab [ 41].
In fact, the only two positively selected variants QUASI identifies in site D are solvent-exposed at the extreme edge of the HA trimer (Fig.