Example sentences for: trichostatin

How can you use “trichostatin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since ERβ bound N-CoR and SMRT in the presence of estrogens, we investigated the possible involvement of corepressors in the actions of agonist-bound ERβ in vivo . To perform this experiment, we examined the effect of the HDAC inhibitor trichostatin A (TSA) on ERβ activity in transiently transfected HeLa cells.

  • Estradiol, diethylstilbestrol (DES), tamoxifen, genistein, coumestrol, thyroid hormone, retinoic acid and trichostatin A (TSA) were purchased from Sigma (St.

  • HDAC inhibitors, such as trichostatin A and trapoxin, modulate gene expression in either a positive, negative or neutral fashion [ 45].

  • Thus, histone deacetylase inhibitors - Butyrate and Trichostatin A - can rescue MHCII-inducibility in bladder carcinoma cells [ 14 ] and restore constitutive MHCII expression in plasmacytoma cells [ 35 ] . In addition to acetylation, transcriptional activity of chromatin is also regulated through phosphorylation (reviewed in Ref.


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