Example sentences for: tree-building

How can you use “tree-building” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • With the complete genome sequences at hand, it appears natural to seek for alternatives to traditional, alignment-based tree-building in the form of integral characteristics of the evolutionary process.

  • The tree topology was then optimized by local rearrangements using PROTML, a maximum likelihood tree-building program, included in the MOLPHY package [ 32].

  • The most straightforward version of this type of analysis, to which we hereinafter refer to as 'genome-tree' building, involves scaling-up the traditional tree-building approach and analyzing the phylogenetic trees for multiple gene families (in principle, all families represented in many genomes), in an attempt to derive a consensus, 'organismal' phylogeny [ 3 4 5 ] . However, because of the wide spread of horizontal gene transfer and lineage-specific gene loss, at least in the prokaryotic world, comparison of trees for different families and consensus derivation may become highly problematic [ 6 7 ] . Probably due to all these problems, a pessimistic conclusion has been reached that prokaryotic phylogeny might not be reconstructable from protein sequences, at least with current phylogenetic methods [ 4 ] .

  • Sequences not spanning at least 95% of the partial alignment were excluded from initial tree-building and then added back into the final free using BLASTP based similarity estimates (see Materials and methods).


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