Words similar to traf
Example sentences for: traf
How can you use “traf” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results show that late pre-osteoclasts are capable of signaling via JAK-STAT1, and suggest that signaling events distal to TRAF6 and STAT1 modulate the resistance of these cells to IFN-γ.
Thirteen genes were previously mapped to this region (RU2AS, MRS2L, GPLD1, SSADH, KIAA0319, TRAF, HT012, FLJ12619, Geminin, KIAA0386, Cyclophilin A, CMAH, and NUP50) and are present on the NCBI accession view (NT_017021) of 6p21.
Since it is well established that RANK signaling is mediated primarily through TRAF6 [ 35 ] and that IFN-γ signaling is mediated primarily through STAT1 [ 36 37 ] , we examined their expression by western blot.
Behçet's disease is an autoimmune disorder characterized by a systemic vasculitis that affects the joints, all sizes and types of blood vessels, the lungs, the central nervous system, and the gastrointestinal tract [ 38 ] . There is evidence for linkage with markers spanning nearly 28 Mb of 6p with JA04 in the middle [ 18 ] . Candidate genes for Behçet's would include those expressed in lymphocytes or perhaps bone marrow such as AP3 and FLJ12671 and other immune related genes such as TRAF and RU2AS.
The Toll-like receptor family [ 49], which has evolutionary roots throughout invertebrate metazoans for pattern-based recognition of bacterial and fungal cell-surface components [ 50], activate NFκB through convergent pathways involving the IL-1 receptor-associated kinase (IRAK), the adaptor protein MyD88, TRAF6, NFκB-inducing kinase (NIK), and IκB kinase (Iκk) [ 51].
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