Example sentences for: top-down

How can you use “top-down” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This "bottom-up" approach provides a more accurate representation of regional benefits estimates than a comparable "top-down", emissions-weighted approach might, particularly given the importance of long-range transport for the major pollutants controlled by the Clear Skies Act (SO2 and NOx, as well as mercury).

  • One of the first parallel plate flow chamber described to study neutrophil adhesion to endothelium was described in 1987 by Lawrence et al [ 7 ] . Initially, several investigators produced chambers identical to or very similar to this design, and over the years this initial design has been the most widely used [ 8 ] . This design allowed for study of leukocyte-endothelial interaction from a top-down view and under laminar flow that occurs in the post-capillary venules, the physiologically relevant site for most leukocyte emigration.

  • As a spur to improvements in the system, given the slow pace of top-down efforts at reform, it seems worth trying out in different ways, but it shouldn't be considered a cure-all, especially for the worst-off schools.

  • ‘The distinctions I make are much more between top-down and bottom-up.

  • Progress in digital microscopy has allowed quantitative image analysis to generate data that objectively and completely describe tissue phenotype, free of observer disagreement [ 13 ] , and with the potential to detect subtle changes that are undetectable to the human eye [ 14 ] . Tissue histomorphometric profiles in EMeRGE are correlated statistically with gene-expression profiles, characterizing each sample through both top-down phenotypic information and complementary bottom-up genomic data.


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