Example sentences for: toluene

How can you use “toluene” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some of the most comprehensive and sophisticated human PBPKs have been developed to describe the pharmacokinetics of volatile toxic solvents such as toluene [ 32 44 45 ] , styrene [ 46 47 ] , and methyl chloride [ 48 ] . The most involved models incorporate several different fat and muscle compartments with different flows and allow for changes with time in the blood flows as the subject's exercise level varies [ 45 47 48 ] . These studies have also introduced a Bayesian approach to determine the population distribution of the PBPK parameters [ 45 47 ] . PKQuest cannot complete with these PBPKs for this class of solutes.

  • However, since there is little direct information about human lung metabolism of toluene, it was assumed here that only the liver was involved in the metabolism.

  • The toluene data was based on the published investigation of Pierce et al.

  • toluene_15:=proc()

  • Since the value of the oil/water partition coefficient varies from 3 for nitrous oxide to 120 for toluene, the ability of PKQuest to model these different solutes using a single set of organ fat fractions (klip) demonstrates the generality of this approach.


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