Words similar to toluene
Example sentences for: toluene
How can you use “toluene” in a sentence? Here are some example sentences to help you improve your vocabulary:
Enflurane, nitrous oxide, halothane and toluene
The rat liver has a number of enzymes involved in toluene metabolism [ 49 ] . Since the Km for all of these enzymes is in the mM range, while the blood toluene concentrations for this data are in the μM range, it was assumed that the metabolism is linear which, in PKQuest, is indicated by using Tclr (in place of Vm and Km).
For solutes such as toluene [ 45 67 ] , styrene [ 47 ] and methoxyflurane [ 58 ] there is, at first glance, a peculiar asymmetry in the data that has caused some confusion: during uptake there is a large difference in the end tidal and arterial partial pressures, while, during washout, there is only a small or negligible difference.
For extremely soluble solutes such as ethanol (Kbair = 1756), the expired gas concentration is dominated by exchange with the conducting airway and is almost independent of the alveolar concentration [ 63 65 ] . For gases of intermediate solubility, such as styrene (Kbair = 48) or toluene (Kbair = 18) the effect is less dramatic and has often been overlooked.
Some of the most comprehensive and sophisticated human PBPKs have been developed to describe the pharmacokinetics of volatile toxic solvents such as toluene [ 32 44 45 ] , styrene [ 46 47 ] , and methyl chloride [ 48 ] . The most involved models incorporate several different fat and muscle compartments with different flows and allow for changes with time in the blood flows as the subject's exercise level varies [ 45 47 48 ] . These studies have also introduced a Bayesian approach to determine the population distribution of the PBPK parameters [ 45 47 ] . PKQuest cannot complete with these PBPKs for this class of solutes.
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