Words similar to toll-like

Example sentences for: toll-like

How can you use “toll-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

In addition, the genes activated by TCR, costimulatory receptors and IL-2 must be distinguished from those activated by IL-1, IL-6, IL-12, and TNF-α, as well as the genes regulated by the Toll-like receptors (TLR), all of which have been identified as mediators of lymphocyte activation events that were previously ascribed to LAF.
In Drosophila , the prototypic homolog of the mammalian Toll-like receptors (Toll) defends against fungal infection [ 18], whereas the protein 18-wheeler defends against bacterial infection [ 19].
The Toll-like receptor family [ 49], which has evolutionary roots throughout invertebrate metazoans for pattern-based recognition of bacterial and fungal cell-surface components [ 50], activate NFκB through convergent pathways involving the IL-1 receptor-associated kinase (IRAK), the adaptor protein MyD88, TRAF6, NFκB-inducing kinase (NIK), and IκB kinase (Iκk) [ 51].
We recently identified the Lps locus through positional cloning [ 10] and showed that the LPS-resistance phenotype was caused by defects in the Toll-like receptor 4 gene ( Tlr4 ) [ 11].
In light of recent developments in understanding the biology of Toll-like receptors, the NFκB-dominated responses we observe fit well within a model in which undifferentiated, subconfluent Caco-2 cells can recognize Gram-positive cell-surface moieties and induce what is termed an 'innate immune response'.