Example sentences for: toll-like

How can you use “toll-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We recently identified the Lps locus through positional cloning [ 10] and showed that the LPS-resistance phenotype was caused by defects in the Toll-like receptor 4 gene ( Tlr4 ) [ 11].

  • The Toll-like receptors TLR2 and TLR4 are known to be present on a number of different human intestinal epithelial cells, including primary cells, H4 and Caco-2 cells [ 52, 53, 54].

  • The Toll-like receptor family [ 49], which has evolutionary roots throughout invertebrate metazoans for pattern-based recognition of bacterial and fungal cell-surface components [ 50], activate NFκB through convergent pathways involving the IL-1 receptor-associated kinase (IRAK), the adaptor protein MyD88, TRAF6, NFκB-inducing kinase (NIK), and IκB kinase (Iκk) [ 51].

  • In addition, the genes activated by TCR, costimulatory receptors and IL-2 must be distinguished from those activated by IL-1, IL-6, IL-12, and TNF-α, as well as the genes regulated by the Toll-like receptors (TLR), all of which have been identified as mediators of lymphocyte activation events that were previously ascribed to LAF.

  • In Drosophila , the prototypic homolog of the mammalian Toll-like receptors (Toll) defends against fungal infection [ 18], whereas the protein 18-wheeler defends against bacterial infection [ 19].


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