Example sentences for: tolerability

How can you use “tolerability” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the long term tolerability and efficacy of HAART has not been studied in patients on dialysis.

  • Future prospective studies are required to determine efficacy and tolerability of HAART and ACE inhibitors in patients with HIVAN and ESRD.

  • It also explains some aspects of mefloquine's tolerability profile in travellers which until now have not been understood, notably that young women experience more adverse effects from mefloquine than men, and that children and older adult travellers (who do not use oral contraception, and who rarely misuse alcohol) seem to tolerate the drug well.

  • To reduce APV pill burden and possibly improve tolerability of APV treatment, pharmacokinetic research efforts have been directed at combining APV with the PI ritonavir (RTV), which inhibits CYP3A4-mediated hepatic metabolism of APV, thereby enhancing plasma APV exposure [ 13 14 15 ] . The administration of RTV at the clinically sub-therapeutic dosage of 100 mg BID was found to boost APV plasma exposure to such a degree as to permit halving the APV daily pill burden from 16 to 8 capsules/day, in addition to maintaining the minimum plasma APV concentration (C min ) over 24 hours well above the 50% inhibitory concentrations (IC 50 ) of patient-derived HIV-1 isolates [ 15 ] . A pharmacokinetic study in 20 HIV-infected patients, PROF1004, showed that APV at the lower dosage of 600 mg BID combined with RTV 100 mg BID (APV600/RTV) resulted in a geometric mean steady-state APV C min (1.

  • Saltissi, et al [ 11 ] recently reported the tolerability and effectiveness of simvastatin in doses of 5-20 mg in lowering LDL and non-HDL cholesterol in dialysis patients.


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