Example sentences for: thymus

How can you use “thymus” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The existence of X-chromosome inactivation in females offers a potential mechanism whereby X-linked self-antigens may escape presentation in the thymus or in other peripheral sites that are involved in tolerance induction.

  • Our results show that fetal and adult wild type thymocytes have stage-specific differences in proliferation, with both TN1 and DP cells exhibiting higher levels of proliferation in fetal thymus.

  • Consistent with this idea, the positive and negative selection in the thymus of CD5-deficient mice is altered in that their thymocytes are hyperresponsive and hyperproliferative to activation induced by anti-CD3 antibodies [ 17].

  • Thymocyte development occurs within a complex network of cells, extracellular matrix, and secreted factors referred to as the thymic microenvironment [ 1 ] . Current evidence suggests that this microenvironment is created during fetal thymus organogenesis through stage-dependent interactions between differentiating thymic epithelial cells (TECs) and developing thymocytes [ 2 3 4 5 6 ] . Therefore, blocks at different stages of thymocyte development result in differential effects on TEC differentiation and function.

  • AlphaB was found to be expressed at significant levels in a variety of nonlenticular tissues, while alphaA has only been detected in small amounts in a few other tissues such as retina, spleen and thymus [ 8 9 10 11 12 ] . Collectively, these findings have challenged the dogma that alpha-crystallin is purely a structural protein necessary for light refraction, and have led to the realization that alpha-crystallin may have a variety of biological functions in the lens.


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