Example sentences for: thiorphan

How can you use “thiorphan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The two experimental groups received intrathecally 10 μl of a mixture containing 10 μM of thiorphan and 20 μM of kelatorphan (to delay the degradation of the peptide ligand) and 10 μM of dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH 2 , Sigma, a selective δ agonist ( 14, 34)), in 0.9% NaCl.

  • No visible redistribution of anti-id mAb immunoreactivity was observed in response to kelatorphan and thiorphan.

  • without dermenkephalin) in NaCl for 15 and 30 minutes to check if the endogenous enkephalins protected by kelatorphan and thiorphan could, by themselves, induce receptor internalization.

  • Dermenkephalin is markedly increased in potency in the presence of peptidase inhibition -more than one hundred fold with a cocktail of bacitracin, bestatin, and captopril- as in Kramer's study ( 20), and to a greater extent with kelatorphan and thiorphan as used in the present study.

  • Nevertheless, it seems that under our experimental conditions, even if more enkephalin was released by the kelatorphan, and this enkephalin was selectively protected from degradation by thiorphan, no receptor endocytosis was observed in response to endogenous enkephalin.


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