Words similar to thapsigargin
Example sentences for: thapsigargin
How can you use “thapsigargin” in a sentence? Here are some example sentences to help you improve your vocabulary:
2%), thapsigargin (1 μM), glutamate (1 μM) and CaCl 2 (1.
thapsigargin) on the ER Ca 2+-ATPase results in a decrease in the rate of calcium influx across the ER membrane.
Mefloquine also antagonized the subsequent transient elevation of cytoplasmic calcium induced by the addition of thapsigargin as can be seen from examination of the second series of peaks in Figure 1. A subsequent addition of glutamate failed to elicit a calcium response, whereas addition of calcium chloride to the medium did.
The most reasonable interpretation of these data is that mefloquine mobilizes a thapsigargin-sensitive calcium pool, and, since thapsigargin is known to mobilize the ER calcium pool, that this is also the case for mefloquine.
The effect of mefloquine (10 or 80 μM for 5 min), before and after pretreatment with thapsigargin (4 μM for 5 min), on the viability of rat neurons was assessed as described above.
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