Words similar to thalidomide
Example sentences for: thalidomide
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There are a number of effective options available for the alleviation of NVP, varying from non-pharmacological strategies such as diet and lifestyle changes to pharmacological treatments such as Diclectin ®(doxylamine/pyridoxine) [ 5 ] , antihistamine H1 blockers [ 6 ] , phenothiazines [ 7 ] , as well as pyroxidine (vitamin B6) alone [ 3 8 ] . The thalidomide tragedy of the 1960's as well as the Bendectin ®unfounded scare of the mid 1980's [ 9 10 ] has caused women with NVP to look on drug-based strategies with great caution due to concerns over the perceived teratogenicity of these drugs [ 4 11 ] , even when data exist documenting safety [ 5 9 10 ] . Accordingly, non-pharmacological strategies to alleviate NVP may be popular choices amongst pregnant women.
It appears from the different clinical trials with endostatin, thalidomide, the synthetic inhibitors of MMPs, and the different anti-VEGFs that angiostatics, though slightly effective in advanced diseases, are more likely indicated in combination with chemotherapy or radiotherapy and as an adjuvant therapy to treat small tumour masses, in particular local minimal residual disease or micrometastasis.
An article tracks the ongoing fight to get Food and Drug Administration approval for thalidomide, the drug that caused thousands of birth defects in the 1960s.
The Food and Drug Administration approved thalidomide as a treatment for leprosy complications.
Because thalidomide induced gross defects in rabbits but not in rats, these guidelines called for toxicity tests in two species.
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