Example sentences for: thalassemia

How can you use “thalassemia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Until such a study becomes available, we present this comprehensive and quantitative review of the evidence to aid patients with thalassemia major and their physicians in clinical judgment and treatment decisions.

  • Measurement of HIC has been established in the field as the reference method for assessing total body iron burden in thalassemia major, and therefore preferred for research purposes.

  • The National Library of Medicine's computerized bibliographic database (Medline 1966 to December 1999) was searched using a combination of the following keywords: thalassemia, serum ferritin, urinary iron excretion, hepatic iron, liver, chelation therapy, iron chelation, iron chelating agents, desferal, desferrioxamine, deferoxamine, L1 oral chelate, deferiprone and 1,2-dimethyl-3-hydroxypyrid-4-one.

  • While no one method is superior for all clinical scenarios, until recently measurement of hepatic iron stores - through liver biopsy or magnetic susceptometry - has provided the most quantitative, specific and sensitive method for determining the body iron burden in patients with thalassemia major and was considered the reference method for comparison with other techniques [ 2 4 ] . In the future, the newer advanced magnetic-resonance techniques, which allow for the assessment of both liver and cardiac iron, might provide an even more accurate assessment of total body iron [ 5 ] . Measurement of the magnitude of iron loading is useful in evaluating the effectiveness of the chelating agent, calibrating patient-specific treatment, and, in clinical research, as a determinant of clinical outcome.

  • We undertook a quantitative review of the literature to estimate the effectiveness of desferrioxamine and deferiprone in decreasing hepatic iron concentrations (HIC) in thalassemia major.


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