Words similar to thalassemia
Example sentences for: thalassemia
How can you use “thalassemia” in a sentence? Here are some example sentences to help you improve your vocabulary:
It has been said that a meta-analysis is only useful until the next good trial comes along [ 29 ] . In the case of iron chelation therapy for patients with thalassemia major, the addition of any good prospective randomized control trial documenting the impact of treatment on body iron (hepatic and/or myocardial) would contribute measurably to the evaluation of the long-term implications of treatment with deferiprone, compared to desferrioxamine.
All studies of desferrioxamine and deferiprone usage in thalassemia major patients - whether randomized, blinded, comparative, case series, or cross-over - irrespective of language were considered eligible for inclusion in the analysis.
Measurement of HIC has been established in the field as the reference method for assessing total body iron burden in thalassemia major, and therefore preferred for research purposes.
While no one method is superior for all clinical scenarios, until recently measurement of hepatic iron stores - through liver biopsy or magnetic susceptometry - has provided the most quantitative, specific and sensitive method for determining the body iron burden in patients with thalassemia major and was considered the reference method for comparison with other techniques [ 2 4 ] . In the future, the newer advanced magnetic-resonance techniques, which allow for the assessment of both liver and cardiac iron, might provide an even more accurate assessment of total body iron [ 5 ] . Measurement of the magnitude of iron loading is useful in evaluating the effectiveness of the chelating agent, calibrating patient-specific treatment, and, in clinical research, as a determinant of clinical outcome.
The National Library of Medicine's computerized bibliographic database (Medline 1966 to December 1999) was searched using a combination of the following keywords: thalassemia, serum ferritin, urinary iron excretion, hepatic iron, liver, chelation therapy, iron chelation, iron chelating agents, desferal, desferrioxamine, deferoxamine, L1 oral chelate, deferiprone and 1,2-dimethyl-3-hydroxypyrid-4-one.
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