Words similar to testicular
Example sentences for: testicular
How can you use “testicular” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is well established that TG mice overexpressing rat ABP [ 22 ] develop a testicular impairment [ 23 24 25 ] leading gradually to a reduced number of germ cells and infertility [ 26 ] . Various theories were proposed to explain the possible mechanisms behind this testicular impairment seen in the ABP-TG mice overexpressing rat ABP.
Preliminary hybridizations were carried out on the arrays with adult mouse testicular RNA from C57BL/6 mice (Figure 2a,b).
Bovine testicular PH-20 enhances TNF sensitivity in L929 cells by increasing the expression of proapoptotic p53 and WOX1 [ 9 10 ] . The ability of Hyal-1 and Hyal-2 to induce the expression of p53 and WOX1 in L929 cells was examined.
TGF-β1 inhibits epithelial cell growth but promotes fibroblast growth [ 15 ] . TGF-β1 inhibition of epithelial cell growth is blocked by bovine testicular PH-20 [ 15 ] . In agreement with our previous observations [ 11 ] , TGF-β1 promoted L929 cell growth by approximately 20% in 24-48 hr (Fig.
These observations are consistent with our previous finding that exogenous bovine testicular hyaluronidase PH-20 enhances TNF cytotoxicity in various cancer cells, and that TGF-β1 blocks the increased TNF cytotoxicity [ 8 15 ] . As summarized in the Figure 8, the underlying mechanisms whereby Hyal-2 induces TNF cytotoxicity appear to be associated with 1) Hyal-2 induction of the proapoptotic WOX1, 2) Hyal-2 migration to the mitochondria during apoptosis, and 3) the prolonged period of IκBα degradation and NF-κB activation in TNF-treated Hyal-2-expressing cells.
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