Example sentences for: tec

How can you use “tec” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Btk is the prototypical member of the Tec family of non-receptor protein tyrosine kinases (PTKs) that includes Bmx, Itk, Tec and Txk [ 2, 3].

  • In contrast, we have recently demonstrated that PI3K inhibitors do not alter activation of Rlk by Fyn, suggesting that the requirements for activation of Rlk by Src family kinases are distinct from the other Tec kinases.

  • In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.

  • 5 in these mutants, from the earliest stages of organogenesis [ 34 ] . Therefore, the TEC defects in these mice would be expected to have different effects on thymocyte proliferation than in Rag mutants.

  • We also analyzed two mutant strains that have either cell-autonomous ( Hoxa3 +/- Pax1 -/-) or non-cell-autonomous ( Rag1 -/-) TEC defects, with blocks at different stages of thymocyte differentiation.


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