Words similar to taxol
Example sentences for: taxol
How can you use “taxol” in a sentence? Here are some example sentences to help you improve your vocabulary:
The cells were extracted for 5 min on ice with 200 μl of 2× detergent extraction buffer (2% of Triton X-100 or DOTMAC, 50 mM Tris-HCl, 10 mM EGTA, 200 mM NaCl, 2 mM MgCl 2 , protease inhibitor cocktail [20 μg/ml aprotinin, 20 μM E-64, 200 μM leupeptin, 200 μM p-amidinophenylmethanesulfonyl fluoride], 2 μM calyculin A, 10 mM sodium pyrophosphate, 2 μM staurosporine, 20 μM phalloidin, and 20 μg/ml taxol).
Force fields and semiempirical methods applied to Taxol
In less polar chlorocarbon solvents, the Taxol structure and other molecules with similar complexity do not appear to be capable of even qualitative ranking by the various methods with respect to energy.
The likelihood that this is correct is accentuated by the fact that Taxol conformational analysis by NMR has never been performed in pure water, but always as a mixture of DMSO-d 6 and D 2 O. [ 5 ] In addition, in anhydrous methanol, a solvent with a high dielectric and the capacity for explicit hydrogen bonding as in water, the polar form goes undetected.
As a consequence of the above considerations, for highly polar molecules like Taxol it is overoptimisitic to expect that conformational searching based on a computational energy criterion will yield results faithful to experiment.