Words similar to taxol

Example sentences for: taxol

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An interesting but fortuitous outcome in this respect is that conformer 4 , the T or butterfly conformer of Taxol, is predicted to be the dominant conformation by MMFF, AMBER* and MM2* under various protocols (Table 2).
Addition of phalloidin, taxol, or PEG did not make a difference either (data not shown).
The cells were extracted for 5 min on ice with 200 μl of 2× detergent extraction buffer (2% of Triton X-100 or DOTMAC, 50 mM Tris-HCl, 10 mM EGTA, 200 mM NaCl, 2 mM MgCl 2 , protease inhibitor cocktail [20 μg/ml aprotinin, 20 μM E-64, 200 μM leupeptin, 200 μM p-amidinophenylmethanesulfonyl fluoride], 2 μM calyculin A, 10 mM sodium pyrophosphate, 2 μM staurosporine, 20 μM phalloidin, and 20 μg/ml taxol).
As a consequence of the above considerations, for highly polar molecules like Taxol it is overoptimisitic to expect that conformational searching based on a computational energy criterion will yield results faithful to experiment.
For Taxol, application of commonly applied force fields as well as the semiempirical methods AM1 and PM3 results in an ordering of conformational energies that is method dependent and mostly inconsistent with experimental data.