Words similar to tautomycin
Example sentences for: tautomycin
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For example, the characteristic IC 50 values for OA fall in the range: PP2A, 1-5 nM, PP1, 20-80 nM, whereas PP2B is highly resistant to both [ 2 3 7 ] . In contrast, tautomycin affects PP1 and PP2A nearly equally, but fails to inhibit other phosphatases [ 8 ] .
Similar values were recently obtained for Arabidopsis PP1 [ 8 ] . PfPP1 was also inhibited by tautomycin, I-1, I-2, and OA with IC 50 values of 0.8, 400, 7, and 100 nM, respectively (Fig.
As mentioned, PP1 is a highly conserved enzyme, and toxin-sensitive Ser/Thr phosphatase activities are also found in erythrocytes [ 15 ] . Thus, use of PP1 inhibitors, such as okadaic acid or tautomycin (Fig.