Words similar to tandem
Example sentences for: tandem
How can you use “tandem” in a sentence? Here are some example sentences to help you improve your vocabulary:
In keeping with this hypothesis, duplicated genes in a tandem arrangement typically represent more recent duplication events (Friedman and Hughes 2003).
Different sets of polypeptides were found associated with YLR106p in a systematic study of the yeast proteome [ 3 4 ] . In a survey of the family of AAA ATPases, Neuwald and coworkers [ 5 ] noted that YLR106p is a member of the AAA ATPase family and is unusual in containing six tandem copies of the set of sequence motifs that characterize an AAA protomer.
The siRNAs are incorporated into a macromolecular complex which carries out degradation of homologous RNA sequences [ 14 ] . Dicer action serves to inhibit viral infection and retroposon movement, and also plays a role in developmental pathways by cleaving precursors to small regulatory RNAs (reviewed in [ 14 15 ] ). The predicted sequence of the mouse Dicer polypeptide exhibits a single dsRBM and tandem catalytic domains.
The M6P/IGF2R is also mechanistically involved in the genesis of human cancer [ 6 20 21 22 23 24 ] . M6P/IGF2R loss of heterozygosity coupled with intragenic loss-of-function mutations in the remaining allele is a common event in human cancers [ 6 20 21 22 ] . Inheritance of a tandem repeat polymorphism in the 3' UTR of M6P/IGF2R furthermore predicts for enhanced susceptibility to oral cancer [ 25 ] . Moreover, tumor cell growth is inhibited when M6P/IGF2R expression is restored to normal while it is increased when gene expression is reduced [ 26 27 28 29 ] . The results of these mutational and functional studies clearly demonstrate that the M6P/IGF2R possesses the characteristics necessary to be classified as a tumor suppressor gene [ 30 ] .
We did not substantially extend the proximal sequence of chromosome arm 3R in Release 3. The WGS3 assembly extends 774 bp beyond Release 3 and ends in 67 tandem copies of a nearly perfect simple repeat TATAA, a known heterochromatic satellite repeat.
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