Example sentences for: tandem

How can you use “tandem” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since 1983, tax brackets have moved up in tandem with the CPI.

  • Microsatellite fingerprinting exploits the occurrence of variable number tandem repeats (VNTRs) ranging from 1- to 10-bp per repeat, and 1 to >30 repeats per locus.

  • A recent screen for spontaneous duplications in yeast suggests that replication-dependent chromosome breakages also play a significant role in generating tandem duplications, because duplication breakpoints are enriched at replication termination sites (Koszul et al.

  • The smad7 gene contains a perfect palindromic Smad binding element (GTCTAGAC) while the pai-1 and the pthrp promoters harbor AGAC tandem repeats [ 19 33 ] which binds Smad proteins less efficiently [ 34 ] . The upa gene contains only an AP1-binding site which resembles the Smad3/4-responsive AGAC motif [ 35 ] . A weaker binding site could require Smad3 to be present at higher concentrations for efficient binding and would make TGFβ-dependent transcription from a gene more vulnerable to reduced nuclear accumulation of the Smad3 protein.

  • Genetic linkage studies have identified five potential RD loci located on chromosomes 1 [ 1 2 ] , 2 [ 3 4 ] , 6 [ 5 6 7 8 9 ] , 15 [ 7 10 ] and 18 [ 11 ] . The linkage to 6p has been the most often reproduced in independent samples with five studies showing peaks of linkage to different regional marker sets [ 5 6 7 8 9 ] . We recently constructed a BAC/PAC contig of the 6p RD locus [ 12 ] and identified the precise location and order of 29 short tandem repeat (STR) markers spanning this region [ 13 ] . A subsequent study with this new marker panel identified a peak of transmission disequilibrium at marker JA04 (G72384) [ 14 ] .


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