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Example sentences for: takagi

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2001; Takagi et al.
2003) and the extracellular domain (Takagi et al.
This interaction unclasps the complex between the cytoplasmic tails, which then allows a conformational shift in the extracellular domain from a bent to a more extended form for high-affinity ligand binding (Figure 1) (Takagi et al.
Springer and coworkers used a series of biochemical/biophysical experiments to suggest that the bent structure represents an inactive form of integrin (Takagi et al.
On the extracellular side, while the C-terminal unclasping and separation of the cytoplasmic and transmembrane regions appears to relieve the structural constraint and may allow the unbending of the extracellular domain to attain the high-affinity ligand binding state (Takagi et al.