Words similar to tac

Example sentences for: tac

How can you use “tac” in a sentence? Here are some example sentences to help you improve your vocabulary:

To analyse the mechanism of the effect of concomitant therapy of TAC and SRL on lymphocyte proliferation, we studied the mRNA expression of TGF-β, p21, IFN-γ, TNF-α, Il-6, IL-10, cyclins G and E. The results demonstrated a significant increase in TGF-β mRNA expression (p < 0.03) with TAC and SRL.
The long-term treatment of patients with either CsA or TAC results in side effects such as nephrotoxicity, hypertension, and gingival hyperplasia [ 1 2 ] . Sirolimus (SRL) a new immunosuppressive agent is structurally similar to TAC binds to same binding protein FKBP, but its mechanism of action is different [ 3 ] . Both clinical and experimental studies demonstrated that SRL when used either with CsA or alone is associated with side effects such as hyperlipidemia, thrombocytopenia and nephrotoxicity [ 4 5 6 7 ] . Since SRL and TAC have affinity for the same binding site, it was thought to be ineffective when used together.
These results are consistent with our previous studies [ 21 22 ] , that TGF-β mediates in part the immunosuppressive effects of CsA and TAC.
Similarly, a significant decrease (p < 0.01) in Cyclin E mRNA was noted with TAC and SRL (0.
23 ± 0.05) compared to patients treated with TAC/MMF/Aza (0.