Words similar to sα

Example sentences for: sα

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Based on this unique localization of sα i2 , a prominent role in membrane trafficking has been proposed for this subunit [ 3 ] . However, no report to date has supported a functional role for sα i2 in vesicular transport, although a variety of functional assays have implicated other Gα, including α s and α i3 , in vesicle trafficking pathways [ 1 2 ] .
A splice variant of α i2 , termed sα i2 , has been proposed as a candidate to regulate vesicle transport due to its localization at intracellular membranes.
Immunoprecipitation of the α subunit after increasing times of chase, followed by SDS-PAGE and fluorography revealed that radiolabeled sα i2 was rapidly lost.
Unfortunately, initial attempts to directly show a defect in guanine-nucleotide binding by sα i2 , using a GTPγ S-dependent trypsin protection assay [ 23 ] , were unsuccessful due, at least in part, to the inability to solubilize expressed sα i2 from membranes using a mild detergent ( e.g., lubrol/polyoxyethylene 10-lauryl ether).
In the experiment presented in Figure 10, the t 1/2 was determined to be approximately 90, 180, and 360 min for sα i2 , α i2 A327S, and α i2 , respectively.