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How can you use “sα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Clearly, some aspect of the novel splicing is responsible for the difference in subcellular targeting of i2 ( i.e. , Golgi and intracellular membranes) compared to wild type α i2 ( i.e., PM).

  • In addition, the use of proteasome inhibitors (Figures 7and 9) suggest that i2 is degraded by a proteasome pathway.

  • It seems likely that the C-terminal disruption of i2 (replacing the 24 C-terminal amino acids) is a more severe disruption than the A327S substitution.

  • i2 may exist in a state that does not interact well with βγ simply because it is in the process of being irreversibly inactivated [ 9 10 ] . Similarly, α i2 A327S appears not to be defective in its intrinsic ability to interact βγ [ 10 ] , and co-expression of βγ shifts α i2 A327S, like i2 , from intracellular to plasma membranes (Figure 8).

  • In addition, similarly to i2 , an α i2 mutant, α i2 A327S, previously demonstrated to be unstable in vitro , displays a defect in plasma membrane localization when expressed in cells.


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