Words similar to synovium

Example sentences for: synovium

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Use of the synovium as a target tissue for TGF-β1 gene transfer, resulting in elevating the intra-articular level, is thus not appropriate for the enhancement of repair of cartilage defects.
Inflammation and production of chemokines such as macrophage inflammatory protein-1α and RANTES [ 7 8 ] in the synovium may result in preferential recruitment of such effector memory CD8 +T cells (which are important contributors to IFN-γ production) and subsequent macrophage activation, because terminally differentiated CD45RA +CD62L -CD8 +T cells have been shown to express higher levels of perforin and may be more potent effector cells [ 10 ] . The question arises of whether the observed skewed differentiation of CD8 +T cells in RA patients is due to medication, especially steroids.
In parallel with the study on human primary chondrocytes, we examined the effects of 300 nM CDDO on synovial fibroblasts excised from OA synovium.
In this regard, recent studies [ 31] have suggested that synovial tissue cells were selectively responsive to IL-12 produced in the synovium, because IL-12 induced increased production of IFN-γ, but not IL-2 and IL-4.
It is characterized by a chronic, erosive inflammation of painful and debilitating joints, with progressive degradation of cartilage and bone accompanied by proliferation of the synovium [ 12 ] . Rheumatoid arthritis remains incurable and, in many patients, difficult to treat.