Words similar to sugar-response
Example sentences for: sugar-response
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In addition, a recent report indicates that mannose may affect some processes by sequestering phosphate, rather than by stimulating a hexokinase-mediated sugar-response pathway [ 66 ] . Although the mechanism by which mannose acts is uncertain at this time, the fact that it retards lipid breakdown when present at concentrations of only 1.4 mM indicates that the effects of mannose cannot be attributed to osmotic stress.
Several groups of Arabidopsis mutants that are resistant to the inhibitory effects of high sugar concentrations have been isolated [ 46 47 48 49 50 ] . Characterization of these mutants reveals that the sis5 [ 46 ] , sun6 [ 50 ] , gin6 [ 49 ] and isi3 [ 45 ] mutants are allelic to the abscisic acid insensitive mutant abi4 [ 51 ] and the sis4 [ 46 ] , isi4 [ 45 ] and gin1 [ 45 ] mutants are allelic to the abscisic acid biosynthesis mutant aba2 [ 52 ] . In addition, the ethylene constitutive response mutant ctr1-1 [ 53 ] , as well as the ethylene-overproduction mutant eto1 [ 54 ] , display sugar-resistant phenotypes [ 48 ] . Conversely, the sugar-response mutant sis1 exhibits an ethylene constitutive response phenotype and is allelic to ctr1-1 [ 47 ] . The prl1 mutant, which exhibits increased sensitivity to exogenous sugars [ 55 56 ] , carries a mutation in a gene that encodes a WD protein that interacts with SNF1 protein kinases [ 57 ] .
Additional sugar-response mutants have been identified by taking advantage of the fact that high concentrations of exogenous sugars (glucose or sucrose) inhibit early seedling development of wild-type Arabidopsis.
A number of Arabidopsis sugar-response mutants have been isolated that, unlike wild-type plants, are able to develop substantial shoot systems in the presence of 0.27 to 0.33 M sucrose or glucose [ 46 47 48 49 50 ] . Analysis of a representative mutant of this type, the sis5-1/abi4-101 mutant [ 46 ] , reveals that it is resistant to the inhibitory effects of exogenous glucose on seed storage lipid breakdown.
Genetic approaches are being used to identify additional components of sugar-response pathways.
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