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Example sentences for: sueoka
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Sueoka [ 18 19 ] has computed the RNP for a representative sample of bacteria, all species together, and showed that G+C12 and G+C3 are correlated among bacterial genomes with a slope of 0.25.
We take as our starting points Sueoka's hypothesis that genome composition is largely determined by mutation bias, specifically the ratio of AT→GC to GC→AT mutations [ 3, 29, 32], and Muto and Osawa's demonstration that different types of sequence, and the three codon positions within exon sequences, vary in their response to genome GC content with the third position changing the fastest, which suggests that the different observed substitution rates might be explained by the differential effects of mutation [ 53].