Words similar to subpopulations
Example sentences for: subpopulations
How can you use “subpopulations” in a sentence? Here are some example sentences to help you improve your vocabulary:
This raises the issue of whether the apparent changes in TTP expression were due, in part, to differential rates of margination by leukocyte subpopulations.
It is known that during clonal selection in the thymus, immature CD4, CD8 double positive cells develop into single positive CD4 or CD8 cells according to the relative affinity of their TCR to class II or class I molecules respectively [ 5 6 ] . These immature T-cells are selected in the thymic epithelium on the basis of their TCR interaction with either class I or class II MHC molecules [ 7 8 ] , thus generating two mutually exclusive subpopulations that are characterized by the expression of either CD4 or CD8 glycoproteins [ 9 ] . Earlier studies in the murine system have demonstrated that PMA and cAMP can modulate the expression CD4 and CD8 on developing thymocytes [ 10 11 12 13 ] . In keeping with these findings, ex vivo experiments with human thymocytes previously reported by our group, revealed that while phorbol esters can coordinately regulate the transcription of α and β TCR during intrathymic T cell differentiation [ 14 ] , cAMP selectively affected the transcription of the α and δ-TCR [ 15 16 ] . Together the murine data and our own findings support the hypothesis that in humans, TCR expression and CD4, CD8 commitment and selection may be regulated by the same signal-transduction pathways.
In this study, four human volunteers were infused with LPS and the subsequent changes in leukocyte cell count, TTP expression in leukocyte subpopulations, and levels of TNF were followed over a 72-hour period.
In modeling differential expression levels of genes, it is natural to assume that genes are from two subpopulations, one with constant and another with changed expression levels.
The different values of λ max for pR in membrane state [ 1 ] and OG solution might be related to the presence of these multiple subpopulations, but this connection remains unclear.
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