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Example sentences for: subdomains

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This implies that the insertion may have altered the relative position of the subdomains in the two subunits thereby perturbing the dimer stability.
Each of these subdomains is regulated by a distinct imprinting control element.
The sequence identity within the HisRS domain of IfkA/B and yeast GCN2 is 28%, with strong conservation within the M1, M2, and M3 motifs that are characteristic of class II aminoacyl-tRNA synthetases [ 37 ] . The similarity between the kinase domains is much higher, with IfkA/B possessing 44% identity with yeast GCN2, with high conservation of all of the kinase subdomains.
The blasticidin resistance cassette replaced a 391 bp fragment that includes the first four subdomains (the ATP binding site) of the kinase domain.
Within the amino terminal sequences, yeast and other GCN2 proteins have a degenerate kinase domain of unknown function [ 31 ] . There is a 63 amino acid long sequence in IfkA that has 38% identity to the V and VI subdomains of the IfkA/B kinase domain, indicating the presence of an amino terminal pseudokinase domain in the Dictyostelium protein (fig.