Words similar to sub-micromolar

Example sentences for: sub-micromolar

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The HL-60 human promyelocytic leukemia cell line responds in culture to sub-micromolar concentrations of retinoic acid ( all-trans and 13-cis ) by undergoing terminal differentiation to a granulocytic cell with the ability to phagocytose and reduce nitroblue tetrazolium [ 28 ] . The response to retinoic acid in HL-60 cells is dependent on the expression of the retinoic acid receptor RAR α [ 29 ] . The use of all-trans retinoic acid in differentiation therapy for patients with acute promyelocytic leukemia has resulted in prolonged, complete remissions when combined with cytotoxic chemotherapy, and may provide complete, long-term remissions as a single agent [ 30 ] .
It is to be noted that a chemical is generally considered a promising pharmaceutical if it is effective at sub-micromolar concentrations, (ii) The effect is highly specific: dsRNA against one viral mRNA did not affect other viral mRNAs or the cellular genes tested here.