Example sentences for: sub-lethal

How can you use “sub-lethal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, sub-lethal radiation may reduce antigen-specific immune tolerance mediated by bone marrow-derived cells, including regulatory T cells, in the tumor-draining lymph nodes.

  • In contrast, sub-lethal radiation alone resulted in a significant reduction of tumor burden (63%, p = 0.01).

  • We used two distinctive therapeutic trial designs for the treatment of tumors Rip1-Tag2 mice: intervention and regression [ 33 ] . In each trial we used three experimental arms as well as an untreated control group; the treatment arms were adoptive transfer of tumor antigen specific T cells, a sub-lethal dose of radiation (600R), or radiation followed by adoptive transfer.

  • Second, radiation-induced damage or abnormality may induce a "tissue damage signal" in the solid tumors through radiation-mediated apoptosis [ 38 ] . There is mounting evidence that apoptotic cell death is not immunologically benign, but can trigger immune responses [ 39 40 ] . For example, cells treated with ultraviolet radiation can provide potent adjuvant function in vivo [ 41 ] . Sub-lethal radiation could result in altered expression of pro or anti-inflammatory chemokines [ 42 43 44 ] or increased expression of T cell co-stimlulatory molecules (i.e.

  • Sub-lethal radiation increases lymphocyte infiltration of tumors


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