Words similar to stroma
Example sentences for: stroma
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When the tissue temperature drops to below 40°C, these bonds can reunite with possible rearrangement of the matrix but without any cellular damage [ 16 ] . Under this consideration the thermal contact of the 49°C preheated PALM gel onto the bare corneal stroma for the in situ molding of the lenticule, would not be expected to induce any irreversible changes of the corneal collagen chains.
The cells of interest in the majority of cases were those of epithelial origin, but eight specimens were also used for the isolation of tumor-associated stroma (fibroblast, endothelial and inflammatory cells) for comparison.
TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .
Due to the potential of contaminating the tumor tissue sample with normal stroma, allele loss in informative patients was defined as a >50% decrease in the ratio of the polymorphic band intensities in the tumor tissue versus that in the surrounding normal stromal tissue; this was quantified using a densitometer.
In the tissue, latent MMP-2 was widely expressed in the synovial lining layer and in areas of stromal proliferation in the sublining layer and stroma, whereas MMP-9 was expressed more sparsely and focally.
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