Example sentences for: striatum

How can you use “striatum” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • From a technical point of view the mouse striatum has several advantages that make it an excellent target for complex trait analysis of the mammalian CNS.

  • Second, the dorsal striatum has a comparatively homogenous cellular composition, potentially reducing the number of quantitative trait loci (QTLs) that affect striatal neuron number.

  • We report here both neuroanatomic and genetic quantitative evidence that the size of the striatum and the number of neurons contained within it are modulated independently.

  • A role for BMP-5 in dorsal forebrain patterning has been proposed based on its expression in the dorsal midline of the developing forebrain and observations that ectopic expression of BMP-5 in the developing neural tube of chicks markedly downregulates ventral markers while maintaining dorsal markers [ 5 7 ] . Further support for BMP-5 regulation of early forebrain development has been provided by studies of Bmp5/Bmp7 double mutants [ 6 ] . However, reports that BMP-5 in the mouse brain exhibits peak expression levels in the adult striatum and brainstem and that maximal expression in the hippocampus and cerebellum occurs at E18 through PN1 and again in the mature nervous system [ 3 ] , suggest additional roles for BMP-5 during later stages of neural development and into adulthood.

  • In mapping neuron number we actually used the residual cell population as a trait, and we are therefore confident that this interval has a selective, although not necessarily exclusive, effect on numbers of neurons in striatum (Fig 4B).


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