Words similar to stem-loop

Example sentences for: stem-loop

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Conversely, we consider classes 4-6 to have a low probability of reflecting a genuine miRNA in Drosophila , regardless of how 'impressive' the helical nature of the conserved stem-loop is.
Because the ∈ RNA stem-loop induces a structural change in P that is required for DHBV DNA polymerase activity [ 27, 28], we examined the possibility that ∈ may activate the RNAseH activity in micrococcal nuclease treated cores.
Although most known pre-miRNAs in Drosophila , Caenorhabditis , mice and humans form relatively canonical stem-loops of around 70 to 100 nucleotides in length, plant miRNA precursors are often processed through exceptionally long stem-loops (many 150 nucleotides or longer) [ 14 15 16 ] . miR-125 is a member of the Drosophila reference set that received a low score by our informatic procedure, possibly because it may derive from an unusually long stem-loop (120 nucleotides), only a portion of which was included in the queried window.
The largest cluster of miRNA genes in Drosophila includes six that were previously identified as the mir-3 → mir-6-3 cluster [ 10 ] . We identified two additional conserved stem-loop structures that flank mir-3 (Figure 7a), one of which ( mir-286 ) was confirmed by northern blot (Figure 5a).
Indeed, we tested one class 4 and seven class 5 candidates by northern blot and failed to observe expression for any of them, despite extensive, conserved stem-loop structure (data not shown).