Example sentences for: steady-state

How can you use “steady-state” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The reaction of wild-type L1 with nitrocefin under steady-state conditions at 10°C resulted in a rapid decrease in fluorescence followed by a rate-limiting return of fluorescence (Figure 3A).

  • This is consistent with our previously published finding that steady-state MMP-13 mRNA levels peak 12 hours after IL-1 treatment of chondrocytes [ 11].

  • To reduce APV pill burden and possibly improve tolerability of APV treatment, pharmacokinetic research efforts have been directed at combining APV with the PI ritonavir (RTV), which inhibits CYP3A4-mediated hepatic metabolism of APV, thereby enhancing plasma APV exposure [ 13 14 15 ] . The administration of RTV at the clinically sub-therapeutic dosage of 100 mg BID was found to boost APV plasma exposure to such a degree as to permit halving the APV daily pill burden from 16 to 8 capsules/day, in addition to maintaining the minimum plasma APV concentration (C min ) over 24 hours well above the 50% inhibitory concentrations (IC 50 ) of patient-derived HIV-1 isolates [ 15 ] . A pharmacokinetic study in 20 HIV-infected patients, PROF1004, showed that APV at the lower dosage of 600 mg BID combined with RTV 100 mg BID (APV600/RTV) resulted in a geometric mean steady-state APV C min (1.

  • The steady-state kinetic data generally support the prediction that Asn233 does not play a large role in binding or catalysis.

  • The pre-pulse was delivered from a holding potential of -80 mV, and therefore the pre-pulse current should be less contaminated by steady-state inactivation.


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