Example sentences for: statin-activated

How can you use “statin-activated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Y-27632 showed no effect on basal sAPP α release and blocked statin-activated sAPP α shedding (data not shown).

  • In our paper [2], we present evidence that the isoprenoid pathway contributes to statin-activated shedding of the APP ectodomain in cultured cells.

  • We recently excluded the possibility that either PKC or ERK plays a role in statin-activated shedding [16], raising the possibility that other protein phosphorylation signaling pathways might link statins and/or cholesterol to α-secretase activation.

  • Low doses (<1 μM) of mevalonic acid did not affect statin-induced sAPP α shedding, but complete inhibition of statin-activated sAPP α shedding was achieved with higher doses of mevalonic acid (100 μM).

  • To test whether statin-activated shedding might be attributable to a metabolite downstream of HMGCoA reductase, cells were treated with 1 μM simvastatin, 5 μM FTI-1, and a series of concentrations of mevalonic acid.


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