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Example sentences for: sprague-

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A number of different groups have reported that genetically hypertensive strains of rats (SHR, SHRSP, WKY) have elevated levels of plasma sitosterol [ 15 16 17 18 19 20 21 22 ] . Although the WKY strain is not considered hypertensive, dietary alterations involving plant sterols appear to increase blood pressure in this strain [ 21 ] . We screened two commercially available hypertensive rats, as well as a 'genetically hypertensive' strain, GH, for plasma plant sterol levels and compared these to two control strains, Sprague-Dawley and Wistar (Table 4).
The aortocaval fistula (ACF) [ 18 19 ] was created between the infrarenal abdominal aorta and the adjacent vena cava in male Sprague-Dawley rats weighing 250-300 g.
It is likely that growth inhibition is attributable to metabolic causes arising from both oxygen delivery and mitochondrial insufficiencies associated with iron deficiency [ 14 ] . The growth data for both the control and iron deficient groups are also similar to that reported for male Wistar rats fed an iron and copper deficient diet [ 15 ] , but the iron deficient rats at 52 days of age were larger than reports of 10 week old Harlan Sprague-Dawley rats fed an AIN-76 iron deficient diet [ 17 ] .
Animals used in these experiments were male Sprague-Dawley rats (260-300 gm).
Intact female Sprague-Dawley rats were used at 6 weeks of age (136 ± 3 g body weight at fracture) or at 12-15 months of age (309 ± 6 g at fracture).