Words similar to spo

Example sentences for: spo

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Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).
Presence of four introns suggested that the rec12 +cDNA encodes a protein of 345 amino acids with high homology to eukaryotic Spo11 proteins (Figure 1B).
Conserved structure and function of Rec12 (Spo11) to initiate recombination
We used dosage studies to see if Rec12 functions in a manner predicted by homology to Spo11/Top6A.
Alignment of Rec12 with other Spo11 family members