Words similar to spleen

Example sentences for: spleen

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Previous studies have shown that adoptively transferred tumor antigen-specific CD4 +T cells can be tolerized in the secondary lymphoid organs [ 9 34 ] , including the RIP-Tag2 model [ 30 ] . Radiation may kill or disable regulatory T cells [ 35 36 ] , or other bone marrow-derived tolerizing cells and prevent the induction of tolerance in adoptively transferred tumor-specific T cells [ 9 ] . Additionally, the high but sub-lethal dose of radiation used leads to significant lymphopenia [ 37 ] . The sudden reduction in lymphocyte number may create the spatial allowance in spleen and lymph nodes necessary for the homing, activation and expansion of he adoptively-transferred T cells.
The CD4 +CD25 +regulatory T cells do not protect SCID mice from arthritis when they are cotransferred with spleen cells from arthritic mice and proteoglycan into SCID mice.
Intravenous administration of the enzyme produced objective clinical improvement (such as reduced liver and spleen size and increased hemoglobin levels and platelet counts).
Thus, in this population a positive correlation between malaria and splenomegaly was observed as recorded elsewhere [ 18 19 ] . However, it requires the services of a medical specialist who is not certain whether the spleen is entirely due to malaria.
Western blotting of mouse tissue extracts detected a 45 kD protein that was present most abundantly in the testis, and to a lesser degree in spleen, liver, lung and brain (Figure 4).