Words similar to splanchnic
Example sentences for: splanchnic
How can you use “splanchnic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Relative hypovolaemia appears to be the most likely explanation for the reductions in cardiac output and splanchnic blood flow observed in animal studies.
Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
Similarly, in humans without ALI or ARDS, PEEP reduces splanchnic oxygenation and this is accompanied by decreases in cardiac output, albeit with no change in lactate levels [ 14 ] . Recently, Kiefer and colleagues [ 9 ] reported no change in splanchnic perfusion when PEEP was titrated on the linear portion of the pressure-volume curve in patients with ALI [ 9 ] .
The results of the present study indicate that incremental increases in PEEP do not impact on splanchnic perfusion, as assessed by gastric tonometry, when cardiac output (and consequently DO 2 ) are maintained.
However, a recent study conducted in humans explored the effect of PEEP in patients with ALI [ 9 ] and did not find a consistent effect on splanchnic blood flow.
Loading...