Words similar to spinocerebellar
Example sentences for: spinocerebellar
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Although the formation of intranuclear inclusions has not been observed in previous studies of Ras-related GTPases, it is a common feature of several neurodegenerative disorders where abnormal proteins containing poly-Gln tracts are synthesized as a result of CAG codon expansions [ 52 ] . Examples include Huntington's disease (huntingtin) [ 53 54 ] , spinocerebellar ataxia (SCA) types 1 and 3 (ataxin-1 and ataxin-3) [ 55 56 ] and dentatorubral-pallidoluysian atrophy (atrophin-1) [ 57 ] . These poly-Gln protein aggregates typically contain ubiquitin [ 58 ] and members of the Hsp70 chaperone family [ 59 ] , consistent with a proposed pathway for cellular clearance of toxic misfolded proteins.
1A,1B,1C), the dorsal spinocerebellar tract (Fig.
SCA8 , an untranslated transcript implicated in spinocerebellar ataxia type 8, overlaps the 5' translation and transcription sites of KLHL1 , a gene primarily expressed in the cerebellum [ 12].
- DSCT : Dorsal spinocerebellar tract
2C), Finally, single immunoreactive fibers were visualized in the ventral spinocerebellar tract (Fig.